Topical anesthetic agents
These agents may reduce penile sensitivity and excitability and delay ejaculation. Condoms also reduce male sensitivity, yet no
evidence shows that wearing a condom helps successfully treat premature ejaculation. Topical anesthetic cream is probably the lowest-risk medication that can be used for premature ejaculation, with no adverse systemic effects in the absence of prior hypersensitivity to the medication (patient or partner). Usually, no contraindication therapy with topical anesthetics.
Lidocaine 2.5% and prilocaine 2.5% (EMLA)
Both of these agents are extremely effective in men in cream ,spray
or ointment form.
